Haematological Malignancies

UCB transplant success in adult leukaemics

18/06/2010 | Unrelated donor umbilical cord blood transplants mismatched for either one or two human leucocyte antigens are as effective in adult patients with leukaemia as allele-matched bone marrow or peripheral blood progenitor cell transplants, a US study has shown.


Next-generation kinase inhibitors show promise first-line in CML

08/06/2010 | The kinase inhibitors nilotinib and dasatinib, previously approved as second-line treatments after imatinib failure in chronic myeloid leukaemia, are also highly effective in first-line treatment, according to two new studies presented at ASCO.


Bioassay could improve outcomes in chronic CML

06/05/2010 | A bioassay that can predict response to imatinib in patients with chronic phase chronic myeloid leukaemia could be used to individualise dosage and improve long-term outcomes, Australian researchers say.


Single dose growth factor comparable to daily dose

19/02/2010 | A single dose of pegfilgrastim administered once per chemotherapy cycle is comparable to daily injections of filgrastim and may be more beneficial for paediatric sarcoma patients receiving myelosuppressive chemotherapy, researchers conclude.


Funeral workers have higher risk of leukaemia

26/11/2009 | Funeral industry workers who are exposed to formaldehyde have an increased risk of mortality from myeloid leukaemia, a study finds.


Low-dose dexamethasone better with lenalidomide

22/10/2009 | Lenalidomide plus low-dose dexamethasone is associated with better short-term overall survival and lower toxicity than lenalidomide plus high-dose dexamethasone in patients with newly diagnosed myeloma, a study finds.


Re-vaccination compliance poor

01/10/2009 | Less than half of Australia's young cancer survivors are receiving booster vaccinations post-chemotherapy and are at increased risk of vaccine preventable diseases, researchers find.


Dexamethasone-based therapy improves survival in childhood ALL

10/09/2009 | High survival rates in childhood acute lymphoblastic leukaemia can be achieved with treatment regimens that are associated with few long-term side-effects, including the omission of prophylactic cranial irradiation, a study finds.


Limiting radiation reduces breast cancer risk in Hodgkin's survivors

13/08/2009 | Women treated with radiation therapy for Hodgkin's lymphoma before age 41 are at high risk for breast cancer but a reduction in radiation volume can lower this risk, researchers report.


Stroke in lymphoma linked to radiotherapy

02/07/2009 | Patients treated for Hodgkin lymphoma with radiation therapy were more than twice as likely to suffer from stroke later in life, according a retrospective study by Dutch researchers. 1 comment


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