There is little evidence that pre-operative MRI improves outcomes for breast cancer patients, according to a new systematic review that also evaluates tool’s place in screening.
Dr Monica Morrow of the US’ Memorial Sloan-Kettering Cancer Center and colleagues carried out an exhaustive review of the past decade’s literature on MRI in breast cancer, looking at over 80 trials, reviews and meta-analyses. Their findings offer a mixed picture of the utility of MRI.
Although MRI screening in BRCA mutation carriers and other high risk women had a higher sensitivity than mammography in all reviewed studies, “the effect of early detection on survival is uncertain”, they wrote.
And in women with breast cancer, pre-operative MRI detected cancer unidentified with other methods, but in two randomised...
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